Mechanisms of PFS (Credit: Alan Jacobs, MD. “Post-Finasteride Syndrome and the Neuroendocrine System.” Presented at the ISHRS 24th World Congress, Las Vegas, Nevada, USA. September 2016.)
| Mechanisms of PFS |
| 1. Testicular functioning is normal. |
| 2. The pituitary gonadotrophs function normally. |
| 3. The hypothalamic GnRH cells may be the area of dysfunction. |
| 4. The temporal lobe limbic structures often inhibit hypothalamic GnRH function. |