Nonsense-mediated mRNA decay (NMD) is a well-studied cellular quality-control pathway. It
decreases the half-lives of eukaryotic mRNAs that aberrantly contain premature termination …

Acetobacter xylinum BRC5 was cultivated in a jar fermentor using glucose as the sole
carbon source. Strain BRC5 oxidized almost all of the glucose to gluconic acid; thereafter, it …

: The trend for treatment of deep second degree burns and third degree burns is toward early
excision and skin grafting. The ability to predict burn depth accurately as early as possible …

Hepatitis C virus (HCV) nonstructural protein 5A (NS5A) has been shown to antagonize
numerous cellular pathways, including the antiviral interferon-α response. However, the capacity …

Molecular patterns in pathogenic RNAs can be recognized by the innate immune system,
and a component of this response is the interferon-induced enzyme RNA-activated protein …

A significant barrier to the therapeutic use of stem cells is poor cell retention in vivo. Here,
we evaluate the therapeutic potential and long-term engraftment of cardiomyocytes (CMs) …

Mitochondria are essential organelles involved in the maintenance of cell growth and function,
and have been investigated as therapeutic targets in various diseases. Recent studies …

Tendinopathy is a common musculoskeletal condition causing pain and dysfunction.
Conventional treatment and surgical procedures for tendinopathy are insufficient; accordingly, …

Nonsense-mediated mRNA decay (NMD) is an mRNA surveillance mechanism that in
mammals generally occurs upon recognition of a premature termination codon (PTC) during a …

In mammalian cells, aberrant transcripts harboring a premature termination codon (PTC)
can be generated by abnormal or inefficient biogenesis of mRNAs or by somatic mutation. …