Skip to main content

Main menu

  • Home
  • Content
    • Current
    • Archive
  • Info for
    • Authors
    • Advertisers
    • Permissions
  • About Us
    • ISHRS
    • Forum
    • Editorial Board
  • More
    • Alerts
    • Feedback
  • Other Useful Sites
    • ISHRS

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Hair Transplant Forum International
  • Other Useful Sites
    • ISHRS
  • My alerts
  • Log in
Hair Transplant Forum International

Advanced Search

  • Home
  • Content
    • Current
    • Archive
  • Info for
    • Authors
    • Advertisers
    • Permissions
  • About Us
    • ISHRS
    • Forum
    • Editorial Board
  • More
    • Alerts
    • Feedback
  • Follow ISHRS on Twitter
  • Visit ISHRS on Facebook
  • Follow ISHRS on LinkedIn
  • Follow ISHRS on Instagram
  • Follow ISHRS on YouTube
Research ArticleArticles

FUE vs. FUT-MD: Study of 1,780 Follicles in Four Patients

Michael L. Beehner
Hair Transplant Forum International July 2016, 26 (4) 160-161; DOI: https://doi.org/10.33589/26.4.0160
Michael L. Beehner
Saratoga Springs, New York USA
MD, FISHRS
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: mlbeehner@saratogahair.com
  • Article
  • Figures & Data
  • Info & Metrics
  • PDF
Loading
  1. Michael L. Beehner, MD, FISHRS (mlbeehner{at}saratogahair.com)
    1. Saratoga Springs, New York USA

Introduction

During the past ten years, there has been a tremendous increase in the use of “follicular unit extraction” (FUE) as a method for harvesting donor hair in hair transplant surgery. Amazingly, this has occurred despite the fact that there are virtually no published, detailed studies showing that the survival of FUE harvested follicles is favorably comparable to those obtained by a strip harvest with microscopic dissection (FUT-MD), which has been the “gold standard” for the past 25 years.

Most hair surgeons familiar with the FUE method agree that the “learning curve” for mastering manual FUE is steep and long in duration. Many of the physicians entering the field in recent years have been led to believe that knowing how to perform FUE will suffice to cover all situations in surgical hair restoration.

Because I felt there was an urgent need for a study comparing the two harvesting methods, I conducted a detailed study of four patients over a 3-year period. All four patients possessed “shiny bald” frontal areas upon which to conduct the study (Figures 1 and 2). In all, 890 FUE follicles were followed along with 890 FUT-MD follicles.

Figure 1.
  • Download figure
  • Open in new tab
  • Download powerpoint
Figure 1.

Study patients 1 (left) and 2 (right): top row, front view; bottom row,

Figure 2.
  • Download figure
  • Open in new tab
  • Download powerpoint
Figure 2.

Study patients 3 (left) and 4 (right): top row, front view; bottom row, top view

To have a better perspective on our study, I feel it is important to define our surgical team’s level of experience at the time we did this study. In late 2012 when we embarked on this research, I and my staff had conducted around 90 FUE surgeries over an 8-year period and felt quite comfortable using James Harris’s SAFE II System. We first harvested FUE grafts using the 3-step manual Harris SAFE System method for 3 years, and then switched to the SAFE II System at that point. Most of our FUE procedures were in the 400-600 range as a supplement to a strip harvest or for obtaining grafts to camouflage a donor scar. I, as the physician, exclusively performed all of the tasks except for trimming and placing the grafts. Our maximum number of FUE grafts for one day had been 1,300. I certainly would concede that some of the very experienced FUE practitioners who have mastered this technique over many years may very well have obtained higher follicle survival percentages than we did. On the other hand, I am quite sure our results were superior to those of the average physician in his or her first couple of years performing FUE. Regardless, this study was embarked upon in order to find out how the two donor harvesting methods stacked up against each other.

Materials and Method

The SAFE II System with the round, dull punch (both 0.9 and 1.0mm diameter) was used for harvesting the FUE grafts. The donor strips were harvested using the classic “one blade” Limmer method, with slivering and the use of 10× stereoscopic microscopes. The 1-hair FUs were placed in 0.8mm slit sites; 2-hair FUs in 1.0mm slits, and 3-hair FUs in 1.1mm sites. All slits were in parallel (sagittal) orientation or slightly oblique off of strict parallel. (See Figure 3.) All tissue and grafts, when out of the body, were kept moist and cool in Plasmalyte solution at 4°Centigrade. Each study box measured 1.1cm × 1.1cm (1.21cm2 area), and a 2mm-wide bald “moat” was left around each box. Light brown tattoo dots were placed at the corners of each box for easy later identification Figure 4).

Figure 3.
  • Download figure
  • Open in new tab
  • Download powerpoint
Figure 3.

Top photo: 3 study boxes immediately post-op; bottom photo: 3 FUE study boxes at 10 months in patient #2

Figure 4.
  • Download figure
  • Open in new tab
  • Download powerpoint
Figure 4.

Single study box isolated and prepared for hair count.

In our first two patients, we created paired boxes for 1-, 2-, and 3-hair grafts. Our third patient had too few natural 1-hair FU donor bundles, and our fourth patient had too few 3-hair grafts, so each of these patients had an extra box of 2-hair FUs to substitute for the missing size grafts.

For each patient, we first harvested the donor strip and sutured it together before harvesting the FUE grafts. The FUE grafts were harvested in the occipital region approximately 2cm superior to the suture line. In each patient, the FUE grafts were placed first before placing the FUT-MD ones.

The first hair counts were performed at 14, 10, 11, and 14 months due to various times the 4 patients were able to return. All of the study grafts for the first two patients were “out of body” around 5-7 hours, which was longer than the 3-4 hour time period for the last two patients, when we made a concerted effort to shorten this interval. On average, for each patient the FUE grafts were out of body around one hour less than were the FUT-MD grafts.

The four patients ranged in age from 27 to 56, with the middle two patients in their mid-30s. None were smokers and none had been using finasteride or minoxidil. For the first two patients, the grafts were all placed by our head nurse (21 years of experience), and for the final two patients, all grafts were placed by me, using a “modified stick-and-place” method, in order to minimize the chance of trauma in the entry phase of planting.

Results

Table 1 below shows the individual results for each patient. Across the board, the FUT-MD grafts survived with higher percentages than the FUE ones. Notable was the fact that patient #1 had very poor growth in all three of his FUE study boxes, and yet his FUT-MD grafts survived relatively well, comparable to the other three patients.

View this table:
  • View inline
  • View popup
TABLE 1. Individual Patient Comparisons

The oldest patient, at age 56, had the overall poorest growth with 61.5% survival of FUE grafts and 76% for the FUT-MD follicles. Patient #3 (35 years of age) had the best overall growth with 74.8% for FUE and 95.2% for FUT-MD.

As shown in Table 2, if all 4 patients’ results are bunched together, there was a 61.4% survival for the 890 FUE follicles and an 86% survival rate for the FUT-MD follicles. If patient #1, the “outlier” with the 33% FUE survival, is dropped, the other three patients had a 70.1% survival rate of FUE follicles and 86.9% survival rate for FUT-MD ones.

View this table:
  • View inline
  • View popup
TABLE 2. Combined Results

Extremely vellous hairs were not counted. Hairs that were somewhat miniaturized were counted and numbered 48 among the FUT-MD grafts and 27 of the FUE grafts. There were 17 grafts that resulted in one additional hair growing beyond the number planted, and these extra hairs were not included in the results tabulated.

In looking at how 1-, 2-, and 3-hair FUs did respectively versus each other with the two harvesting methods, the FUE/FUT-MD results were 58%/86% for 1-hair grafts, 59%/82% for 2-hair grafts, and 66%/91% for 3-hair grafts.

Discussion

Overall, there was a consistent increased survival percentage for the FUT-MD grafts in every pair of the study boxes, despite the fact that they were “out of body” at least 1 hour longer than the FUE grafts. In performing a detailed study like this, unfortunately, time quickly passes while you are carefully trying to perform and record each step properly, and as a result the grafts were out of the body for our first two patients longer than I would have wished, and certainly longer than would occur in most of our day-to-day surgeries.

I would stress the fact that we used great care in carefully placing all of the study grafts, especially the FUE ones, which are more difficult to place due to the loss of fatty surrounding tissue in most of the grafts. In trying to account for the lower survival of the FUE grafts, I would speculate that this tearing off of the surrounding subcutaneous tissue during the “pluck” phase of graft removal would be the prime suspect for this poorer growth (Figure 5). The increased difficulty in graft placement and the potential for desiccation could play a role in this occurrence.

Figure 5.
  • Download figure
  • Open in new tab
  • Download powerpoint
Figure 5.

Study FUE and FUT grafts side-by-side

It should be noted that all of the study boxes were positioned in the middle of a great many grafts, which extended over most of the balding scalp. Placing these boxes by themselves with surrounding “virgin” scalp would presumably have resulted in higher survival rates.

In time, there will certainly be additional studies comparing FUE and FUT-MD grafts. It will be interesting to see if future results are similar to mine or not. It will also be interesting to see if other investigators find occasional patients with extremely poor FUE growth as my first patient showed. I have no way of knowing whether this is a one in a hundred rare occurrence for FUE grafts in any given patient, or whether it will occur more frequently. If the former, then his results should be dropped from my study’s conclusions, and my final results should show a 70.1% survival for FUE grafts and an 86.9% survival for the FUT-MD ones. On the other hand, if it is a more than occasional occurrence, then my study should show that 61.4% of FUE grafts survive in the hands of a moderately competent surgeon and 86.9% for the FUT-MD grafts.

Conclusion

I have heard at least one FUE surgeon state that studies aren’t necessary to prove anything. Manny Merritt showed many years ago that the human eye couldn’t differentiate hair growing at 100% from that growing at only 50%. I think our patients have a right to know if any of their donor hair is being wasted due to the harvesting method chosen. If there is a difference, the patient should be informed before choosing how to proceed.

  • Copyright © 2016 by The International Society of Hair Restoration Surgery
PreviousNext
Back to top

In this issue

International Society of Hair Restoration Surgery: 26 (4)
Hair Transplant Forum International
Vol. 26, Issue 4
July/August 2016
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Ed Board (PDF)
  • Front Matter (PDF)
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on Hair Transplant Forum International.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
FUE vs. FUT-MD: Study of 1,780 Follicles in Four Patients
(Your Name) has sent you a message from Hair Transplant Forum International
(Your Name) thought you would like to see the Hair Transplant Forum International web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
2 + 10 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Citation Tools
FUE vs. FUT-MD: Study of 1,780 Follicles in Four Patients
Michael L. Beehner
Hair Transplant Forum International Jul 2016, 26 (4) 160-161; DOI: 10.33589/26.4.0160

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
FUE vs. FUT-MD: Study of 1,780 Follicles in Four Patients
Michael L. Beehner
Hair Transplant Forum International Jul 2016, 26 (4) 160-161; DOI: 10.33589/26.4.0160
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Introduction
    • Materials and Method
    • Results
    • Discussion
    • Conclusion
  • Figures & Data
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Hair’s the Question
  • Letter to the Editors
  • Graft Survival Using the Pairing Technique: Implications for Placement and Clinical Applications
Show more Articles

Similar Articles

Navigate

  • Home
  • Current
  • Archives

General Information

  • Authors
  • Advertisers
  • Permissions

About

  • ISHRS
  • Forum
  • Editorial Board

Follow Us On

  • Twitter
  • Facebook
  • LinkedIn
  • Instagram
  • YouTube

© 2025 Hair Transplant Forum International

Powered by HighWire